Sheep, Goats & Pigs
100’s of liters of milk per year (not pigs!)
no ill effects on host or offspring, but…
- MT-GH in pigs produced lots of pathology, but...
- IGF-1 in sheep produced more wool
Human hemoglobin in pig blood
- but, hemoglobin needed in human cells!
Pig organs for transplant
- human complement inhibiting protein -- slow rejection
- MHC?, delete major rejection determinants